The Bishop _Bartholomew de Casis_, living a considerable time in _Hispaniola_, in the City _Dominico_, being inform’d of the abundance of Pearls which were caught before _Cubagua_, and the unsupportable cruelty of the _Spaniards_ there under _Ocampus_, us’d against the Inhabitants, went to _Spain_, with a design to obtain of the Emperor _Charles the Fifth_, the Government over _Cumana_ and _Cubagua_, under pretence, to draw the ignorant Natives from their Idolatry, to _Christianity_; which his request was especially promoted by _William_ of _Nassaw_, the Emperors prime Favorite; so that having his Letters Patents granted to that purpose, he took Ship, and arriv’d with three hundred _Spanish_ Gentlemen of Quality in _Cumana_: And that they might have the greater respect shown to them there, they had each a Red Cross given them, such as the Knights of _Calatrava_ generally wear. Yet little did _Ocampus_, the old Governor of _Cumana_, regard either them or their Authority; for in stead of receiving and submitting, he kept the Bishop _de Casis_ out by force of Arms; who then made complaint to the _Vice-Roy_ of the _West-Indies_ in _Hispaniola_, and in the mean time, put his _Cargo_ into a new Store-house. But whilst he made his Addresses, _Ocampus_ having sufficiently inrich’d himself departed, which incourag’d the _Cumaners_, who already were incens’d, and weary of their former sufferings, to venture on a design, whereby they might revenge themselves of the _Spaniards_, which their undertaking prov’d so successful, that very few escap’d the Massacre: Of which, _de Casis_ being inform’d, and much discontented thereat, betook himself to a _Dominican_ Cloyster in _Hispaniola_. [Sidenote: Cruelty of _Castellio_ in _Cumana_.] Yet not long after, the _Cumaners_ paid dear for that slaughter, for one _Castellio_, though not without several Engagements, with various success, lasting forty days together, having at last utterly vanquish’d them, put to an ignominious Death, Hanging up seventy of their Princes, and to them of meaner quality, shewing as little mercy. [Sidenote: _Lampagnano_ discontented.] As little success had _Lodowick Lampagnano_, sent out by some _Spanish_ Merchants, with Letters Patents from the Emperor to Fish for Pearl, before the same _Cubagua_; to which purpose he carry’d peculiar Nets and other necessaries with him. But the _Cubaguan Spaniards_ unanimously withstood him; so that not being able to effect his design, overpower’d with a Melancholly Distemper that broke his Heart, he dy’d. [Sidenote: _Magellanus_ Expedition, how it happen’d.] In the interim, while these scarce considerable Voyages turn’d to so small account, _Ferdinand Magaglianus_ (for so _Peter Martyr_ calls him, and not _Magellanus_, which herein deserves to be credited, because they were intimately acquainted, and great friendship between them,) undertook to Sail round about the World; the occasion of which we will here relate at large: