[82] Mr. _Cleghorn_, while at _Minorca_, after Evacuations, gave the Bark at the End of the third Period, as we observed before; but where the Fever had been neglected till about the third or fourth Period, or badly treated in the Beginning, and the Bowels were inflamed or overcharged with corrupted Gall, he was obliged to endeavour to palliate the most pressing Complaints, and to watch Evening, Night, and Morning for a Remission, and then immediately to fly to the Bark, as the only Remedy that could avert the Danger. If the Patient was strong, he gave Half an Ounce of the Bark, with six Drachms of the _sal catharticum amarum_, divided into four equal Parts, of which the Patient took one every two Hours; the Effect of which was, that the next Fit was mitigated, and an Intermission commonly ensued, in which the Bark was repeated without the Purgative, to finish the Cure.--But where the Patient was excessively feeble, and there was a manifest Risk of his dying in next Fit, he gave Cordials with the Bark, instead of the _sal catharticum_; and endeavoured to throw in six or seven Drachms in the Space of ten or twelve Hours; he having found by Experience, that if a smaller Quantity is given, the Paroxysms come on earlier than usual, and make all Attempts to preserve Life unsuccessful. See his _Account of the epidemic Diseases of Minorca_, cap. iii. 2d edit. p. 192. In _England_, Vernal, Quotidian, and Tertian Agues, frequently go off after Bleeding, and taking some Emetics and Purges, and the saline Draughts, and cooling Medicines, for some Time, without the Use of the Bark; but in _Germany_ very few yielded to this Treatment, and we were obliged to give the Bark[83] before we could put a Stop to them.