An organization which more than any other has distinguished itself for persistent, unwearied, and vigorous attempts to secure reform by legal enactment is the Society for the Prevention of Abuse in Animal Experimentation, organized in Brooklyn, New York, in 1907.[1] From the first it repudiated the suggestion that it was opposed to scientific experimentation upon animals under all circumstances; it has never denied that some benefits have accrued through animal experimentation, even though such benefits have been exaggerated, but it has bent all its energies toward securing such legislation in the State of New York as should limit the practice to competent men, place it under such legal control, render its abuse a misdemeanour, and all unnecessary and wanton cruelty a legal offence. Bills were therefore introduced for the appointment of a Commission of inquiry regarding the extent and nature of the practice at each annual session of the Legislature. Some of these Bills were reported out of the Committee, and one reached debate in the Senate. But investigation of the practice was precisely what the supporters of the modern laboratory do not seem to desire. They were strong enough to influence the Legislature against such inquiry, and their attempts to open the laboratory have so far failed. Will it be possible for ever to maintain this secrecy? That is the question for the future. [1] To the discriminating and energetic work of Frederic P. Bellamy, Esq., the counsel of the society, and of Mrs. William Vanamee, the secretary, the success of this society is particularly indebted. In the public journals, on many occasions, they have definitely and comprehensively outlined the aims of the organization, and in this respect there has been no excuse whatever for any misunderstanding or misstatement. In its early efforts to secure investigation an attempt was made by this society to secure the co-operation of members of the medical profession, and in union with a large number of persons belonging to various professions over seven hundred physicians in the State of New York signed a petition in 1907-08 in favour of a measure that would have tended to elicit the facts. As soon as the Medical Society of the State of New York became aware of this endorsement, it sent out to each of these physicians a request that he would withdraw his name. What Dr. William James called "the power of club influence to quell independence of mind" could hardly have been more significantly exercised, yet less than forty signers were willing to accede to such demand. Upon the files of the society are now the signatures of over six hundred physicians in the State who have favoured legislation restricting the practice of vivisection to competent men, and providing against cruelty and abuse. In the fall of 1911 the Society circulated a petition throughout the State. It asked the Legislature of the State of New York to provide--