SECOND. What is the location of the suspected ailment? When were the first symptoms manifested? To what cause, if any, were they ascribed? Has any surgical operation been performed, and if so, what are the details of time and place? Has recurrence followed operation? For what period was there freedom from symptoms? Whatis the social position of the patient? Does he belong to that class which is enabled always to select the best food, the most sanitary dwellings, and all the conveniences of well-ordered and comfortable existence; or, on the other hand, to the extremely poor class, which disregards cleanliness, indulges to excess in the use of stimulants, and consumes the poorest and cheapest kinds of meat? I deem it of great importance that the completest possible information be secured concerning the usual diet of every sufferer from this disease. Is he a vegetarian? Are viands invariably well-cooked, or eaten sometimes rare or raw? Is there a liking for the canned products of the packing-house, or for sausage that comes from the same source?[1] What is the water-supply? Within the knowledge of the patient or friends, has there been any other case of malignant disease in the same house? Is residence near any fresh-water lake or stream? [1] The relation between diseased meat and human ailments is treated at length in my work on "American Meat," New York, 1909. These are suggestions only. They constitute merely an outline of the information that is necessary, concerning the living sufferers, in whom the disease has made its appearance. Doubtless the average reader will discern no reason for all these inquiiries. Yet each one has some pertinency to the possible discovery of the great secret. Does inquiry concerning family history seem useless? It should have a decided bearing on any theory of heredity. Does the occurrence of near-by cases have no significance? We are not yet in a position to state this as a fact. Does inquiry concerning religion seem especially impertinent? What if some future investigation should prove that cancer everywhere, is more prevalent among the Christians than the Jews? Does the social condition of the sufferer seem to have no relation to cause? What if we discover, that everywhere,--and not among the foreign population of Chicago only,--cancer finds an undue proportion of its victims among the poorest and most poverty-stricken element of every nationality? Does suggestion of inquiry concerning diet induce a smile? It should not, as long as meat derived from cancerous animals is permitted by Government authority, to pass inspection, and to be distributed throughout the world. And no inquiry concerning cancer can be deemed complete which has not fully investigated the extent to which this atrocious practice has been carried on for the past quarter of a century.