It seems to me probable, therefore, that for many years to come, the laboratory for vivisection, IF ONLY IT CAN MAINTAIN ITS SECRECY, will continue as serenely indifferent to criticsm, as completely master of the confidence of modern society, as supreme in power and position as was the Spanish Inquisition of three centuries ago. New laboratories will be founded upon ill-gotten wealth; new inquisitors, with salaries greater than those of Washington or Lincoln will take the places of those that retire; new theories, now unimagined, will demand their tribute of victims to help prove or disprove some useless hypothesis; even new methods of torment may be invented, and new excuses for their necessity put forth. Nor is this all. If the laboratory of the present day shall continue to maintain its hold upon the intelligence of modern society; if it can keep unimpaired that confidence in its benevolent purpose, that belief in accomplishment, that faith in utility which now so largely obtains; and if, moreover, it can secure for the charity hospital that absolute power and secrecy which it has gained for itself in animal experimentation, then, within the lifetime of men now living, human beings will take their place as "material" for investigation of human ailments. Upon the living bodies of Amerian soldiers, upon lunatics in asylums and babes in institutions and patients in charity hospitals, experiments of this character have already taken place. Is utility to Science to be considered the standard by which human actions are to be judged? Then, even within the present century, experimentation upon human beings may be openly acknowledged as a defensible method of investigation. Now all this is not a cry of despair, a confession of defeat. It is meant only to be rational recognition of existing conditions, and especially of the forces that now prevent reform. Perhaps if the armies were united, a different forecast could be made; but that union is beyond hope. The enthusiasm that would expect to eliminate a great evil on other terms, and within the space of time occupied by a single generation does not seem to me to be justified by the records of history. Of the ultimate triumph of the reform of vivisection, there can be no more question than of the result of the agitation against human slavery, against the torment of criminals, against the burning of the heretic or the witch. In what way may we anticipate its coming?