And the Hospital of the Rockefeller Institute for Medical Research, I was enabled to apply the skin reaction to a number of human cases... The total number of cases was 400."[1] [1] Journal of Experimental Medicine, vol.xvi. In the original, the names of the hospitals are somewhat obscured by being placed in brackets, and the paragraph made continuous; they are here printed in capitals, to afford the reader a better opportunity of giving these charitable institutions whatever credit is due them. Four hundred patients in hospitals and dispensaries including the hospital attached to the Rockefeller Institute for Medical Research, were used as "material" for determining the value of a test for latent syphilis. Of these, 146 were healthy individuals, used as "controls." Dr. Noguchi states that these "controls" "include 146 normal individuals, chiefly children between the ages of two and eighteen years; and 100 individuals suffering from various diseasess of a non-syphilitic nature.... In none was a positive luetin reaction obtained." Other experimenters upon human beings have made reports of their investigations in the same direction. A physician of St. Louis in a medical journal, tells us of forty-four cases in which the Noguchi luetin was applied, and he expresses his obligation to eight physicians of that city (naming them), "for the privilege of using THEIR CASES FOR THE WORK."[1] Whether these "CASES" were the private patients of the accomodating physicians, we are not informed. This experimenter had not completed his investigations and announced his intention of "trying it out thoroughly" in a certain St. Louis hospital, which he names. [1] New York Medical Record, May 25, 1912. The same experiments appear to have been made in other institutions. In the Bulletin of the Johns Hopkins Hospital for August, 1912, there appears an account of this luetin test, made upon patients suffering from such ailments as rheumatic fever, typhoid fever and consumption. We see that the practice has extended to some of the leading hospitals of the United States.