"Perhaps no other man in America has so good a right to speak on vivisection, from the standpoint of an expert, as Dr. Leffingwell. To our mind, he has here gathered in a forceful way the last sane word to be said on this sensitive question. In these nineteen chapters he has discussed almost every phase of the problem. Dr. Leffingwell has occupied a difficult position, standing as he does midway between the contending parties.... He discovers the law of cruelty, and applies it mercilessly. He also discovers the law of sacrifice, and would apply it humanely. In short, this book may well be taken as an encyclopaedia on vivisection, looked at from the standpoint of the moralist and the physician. There are illminating appendices giving technical information, and the chapters are characterized by vigorous England, and a lively sense of a physician's obligations." --Chicago Unity "If nothing else in the book were to be remembered, it would be valuable that all earnest people should consider the careful analysis of the various positions which have been taken in regard to this position, and the critical definition with which Dr. Leffingwell has striven to replace the varied and unsatisfactory definitions which have been given for the term `vivisection.' ... The stand taken by Dr. Leffingwell represents the best-founded position of those interested in protecting animals from needless pain. He contends that vivisection should be restricted rather than abolished. There should be no effort made to prevent those experiments which involve no suffering for animals, and all animal experimentation should be brought under the direct supervision and control of the State. `The practice, whether in public or private, should be restricted by law to certain definite objects, and surrounded by every possible safeguard against license and abuse.' That this is not an aim impossible of attainment has been attested by so famous a scientist as Herbert Spencer, and by a large number of prominent American and English physicians and scientists."--Boston Transcript. "It is greatly to be regretted that the general public is not more intelligent on the subject of vivisection. It is charged that to-day, in American physiological laboratories and in medical schools as well, helpless animals are subjected to torture.... The testimony to this seems irrefutable; and one is more disposed to give it credence when he knows of the atrocities that have been perpetrated in other countries, and learns that the practice of vivisection is unregulated here.... "It is fortunate that there is available such a book as that just issued by Dr. Albert Leffingwell, a veteran advocate of legal regulation, not prohibition, of vivisection. Persons who would be conversant with a question that ought to receive much more general consideration than it does should read `An Ethical Problem.'