When Pasteur at the age of fifteen was in Paris, overcome with homesickness, he had exclaimed, "If I could only get a whiff of the old tannery yard, I feel I should be cured." Certainly every time he came in contact with the industries--silk, wine, beer, wool--his scientific insight, Antæus-like, seemed to revive. All his life he had preached the doctrine of interchange of service between theory and practice, science and the occupations. What he did is more eloquent than words. His theory of molecular dissymmetry, that the atoms in a molecule may be arranged in left-hand and right-hand spirals or other tridimensional figures corresponding to asymmetrical crystals, touches the abstruse question of the constitution of matter. His preventive treatment breathes new life into the old dictum _similia similibus curantur_. The view he adopted of the gradual transformation of species offers a new interpretation of the speculations of philosophy in reference to being and becoming and the relation of the real to the concrete. Yet Pasteur felt he could learn much of value from the simplest shepherd or vine-dresser. He was complete in the simplicity of his affections, in his compassion for all suffering, in the warmth of his religious faith, and in his devotion to his country. He thought France was to regain her place in the world's esteem through scientific progress. He was therefore especially gratified in August, 1881, at the thunders of applause which greeted his appearance at the International Medical Congress in London. There he was introduced to the Prince of Wales (_fondateur de l'Entente Cordiale_), "to whom I bowed, saying that I was happy to salute a friend of France." Pasteur's investigation of rabies began in this same year. Difficulty was found in isolating the microbe of the rabic virus, but an inoculation from the medulla oblongata of a mad dog injected into one of the brain membranes (dura mater) of another dog invariably brought on the symptoms of rabies. To obtain attenuation of the virus it was sufficient to dry the medulla taken from an infected rabbit. The weakened virus increased in strength when cultivated in a series of rabbits. Pasteur obtained in inoculations of graded virulence, which could be administered hypodermically, a means of prophylaxis after bites. He conjectured that in vaccinal immunity the virus is accompanied by a substance which makes the nervous tissue unfavorable for the development of the microbe.