To this list we might have added a large number of persons whose brains weighed less than 53 ounces. Yet the brains of Daniel Webster, Agassiz, Napoleon I, Lord Byron, Baron Dupuytren, General Skoboleff, and other famous men concerning whose large brains much has been said, weighed less than this; and we might have appended hundreds of brain weights of idiots, imbeciles, and other insignificant persons, from 53 ounces down to 49 ounces--probably about the average weight in central Europe. In support of our contention is, further, an observation by Dr. Rudolph Wagner in _Nachrichten_, February 29, 1860, pp. 71, 72, that "very intelligent men certainly do not differ strikingly in brain weight from less gifted men." Dr. Clendenning presents in the Croonian Lectures the following entries of brain weights of male subjects of different ages, the tendency of which is to show that the male encephalon loses, after it is grown, more than an ounce every ten years: 15 to 30 years 50.75 ounces. 30 to 50 " 49.66 " 50 to 70 " 47.1 " 70 to 100 " 41.5 " A number of other eminent anatomists have given similar evidence of decrease in brain weight as intellectual power increases. The "Professor at the Breakfast Table," the late Dr. O. W. Holmes, a learned man and experienced physician and professor of anatomy in Harvard University for thirty-five years, says: "The walls of the head are double, with a great chamber of air between them, over the smallest and most crowded organs. Can you tell me how much money there is in a safe, which also has thick walls, by kneading the knobs with your fingers? So, when a man fumbles about my forehead, and talks about the organs of individuality, size, etc., I trust him as much as I should if he felt over the outside of my strong box, and told me that there was a five-dollar or a ten-dollar bill under this or that rivet. Perhaps there is, only he doesn't know anything about it. We will add that, even if he knows the inward dimensions of the strong box, he could not thence determine the amount of cash deposited in it." The internal size of Spurzheim's skull was in cubic inches exactly the same as that of the skull of Joachim, an imbecile six feet nine inches in height, with a brain weight of 61.2 ounces, whereas Spurzheim's brain weighed only 55 ounces. Whoever has examined heads in the dissecting room of a medical college knows that, except in rare cases of disease, the brain does not fit the skull, but is surrounded by three membranes and a watery fluid; and this liquid, it has been ascertained, is generally sufficient to admit of its performing certain movements.