Dr. Pepper realized more and more every year that the vast extent of the university interests demanded the undivided activity of its head. In 1894 he resigned the office of provost, stating at the time that, as it became necessary for him to choose between administration work and medical science, his devotion to the latter determined his choice. His administration was an eventful one, during which the university evolved from a group of disconnected schools to a great academic body. In 1881 its property in land amounted to fifteen acres, while in 1894 it controlled fifty-two acres in a continuous tract. In 1881 the university property was valued at $1,600,000; in 1894 it exceeded $5,000,000. The teaching force in 1881 numbered 88 and the students in all departments 981; in 1894 the former were 268, and the attendance had reached 2,180, representing every State in the Union, as well as thirty-eight foreign countries. Dr. Pepper became well known as an author on medical subjects. He founded the Philadelphia Medical Times, and was its editor for two years. In 1885 he edited a System of Medicine by American Authors, a work that has been considered a leading authority on medical subjects. He also edited a book of medical practice by American authors, and, with Dr. J. F. Meigs, issued a work on Diseases of Children. He was Medical Director of the Centennial Exposition in 1876, and for his services he received from the King of Sweden the decoration of Knight Commander of the Order of St. Olaf. Dr. Pepper showed an unbounded interest in behalf of any movement that would benefit the community in general. He was one of the first to realize the advantage that would accrue to Philadelphia should she become a museum center. The Philadelphia Commercial Museum was established in October, 1893, with Dr. Pepper as president of the board of trustees. The old offices of the Pennsylvania Railroad Company were leased, and exhibits were secured from the Latin-American countries, Africa, Australia, Japan, and India, forming the largest permanent collection of raw products in existence. Referring to the great value of the museum, Dr. Pepper spoke as follows in his address of welcome at the first annual meeting of the advisory board: