regulated according to the strength of the patient and the state of the pulse. After the first four or six hours, more heat need not be applied than is perfectly agreeable to the feelings of the patient. It is remarkable how suddenly the precordial oppression, etc., are relieved on the breaking out of a free perspiration, and, what is of greater importance still, the vomiting, where it exists, immediately ceases." In short, all the urgent symptoms soon subside, and the patient becomes convalescent. Such is Dr. Hawthorne's treatment, which is affirmed to have been invariably successful. It is based on the same general principle as the preceding--a prompt and diffusive stimulant. Here we might ask, What constitutes the chief reliance in the formulæ? Was it the opium that so promptly met and arrested the disease? or the combination of the other powerful stimulants with which it was united? Dr. H. places his main reliance on this drug, and yet affirms that it produced no narcotism or other sensible effect whatever, except as a diaphoretic, and even in this its influence may be questioned. The prognosis becomes favorable from the fact of a sudden rise in the temperature of the body, for the icy-coldness disappeared, the heat of the surface returned, the circulation was equalized and a profuse perspiration set in, and, as these conditions appeared, the urgent symptoms subsided. Not the excessive doses of opium, but the remedies in combination as a whole, produced by its prompt stimulating power these results, and the patient was thus relieved.