In the autumn of 1835 Mr. Dewey was settled over the Second Unitarian Church in New York, trusting to his stock of already written discourses [152] to save him from a stress of intellectual labor too severe for his suffering brain, which was never again to allow him uninterrupted activity in study. When his life-work is viewed, it should always be remembered under what difficulties it was carried on. It was work that taxed every faculty to the uttermost, while the physical organ of thought had been so strained by over-exertion at the beginning of his professional career, owing to a general ignorance of the bodily laws even greater then than it is now, that the use of it during the rest of his life was like that which a man has of a sprained foot; causing pain in the present exercise, and threatening far worse consequences, if the effort is continued. Fortunately, his health in all other respects was excellent, and his spirits and courage seldom flagged. I remember him as lying much on the sofa in those days, and liking to have his head "scratched" by the hour together, with a sharp-pointed comb, to relieve by external irritation the distressing sensation's, which he compared to those made, sometimes by a tightening ring, sometimes by a leaden cap, and sometimes (but this was in later life) by a dull boring instrument. Yet he was the centre of the family life, and of its merriment as well; and his strong social instincts and lively animal spirits made him full of animation and vivacity in society, although he was soon tired, and with a nervous restlessness undoubtedly the effect of disease, never wanted to stay long in any company. [153] He preached a sermon after the great fire in New York, in December, 1835, which drew forth the following letter from Mr. Henry Ware:-- CAMBRIDGE, Jan. 15, 1836. DEAR FRIEND,--I must acknowledge your sermon,-you made me most happy by it. It was so true, so right, so strongly and movingly put; it was the word that ought to be said, the word in season. My feeling was: God Almighty be praised for sending that man there to speak to that great and mighty city, and to interpret to it his providence. You cannot but feel gratitude in being appointed to be such an instrument; and I trust that you are to be used much and long, and for great good. Keep yourself well and strong; look on yourself as having a message and a mission, and live for nothing else but to perform it. I happen to have found out, very accidentally, what is always the most secret of undiscoverable secrets,--that you are asked to preach the Dudleian Lecture. Do not let anything hinder you. We want you: you must come; do not hesitate; and, mind, I speak first, to have you come and house it with me while you are in Cambridge. Pray, deny me not.