But another and very remarkable method of mitigating the virulence of
eel blood, and one which so far has received no explanation, is
mentioned by Dr. Wehrmann, of Moscow, who has been lately studying the
character of this fish's blood in Dr. Calmette's laboratory at the
Pasteur Institute at Lille. Dr. Wehrmann found that if blood serum be
taken from animals previously rendered artificially immune to the
action of serpent venom, and if some of this so-called anti-venomous
serum be injected under the skin of eels some hours before they are
killed, the lethal properties of their blood after death are
considerably reduced. Thus, an eel weighing about six ounces received
subcutaneous injections of five cubic centimetres of anti-venomous
serum; after the lapse of four-and-twenty hours it was killed and
bled, and its serum inoculated into animals in the usual way. But
whereas two cubic centimetres of normal eel blood sufficed to kill a
guinea-pig, this eel's blood had to be administered in _twice_ that
quantity to produce a fatal result, so that its toxic character had
been reduced to a very appreciable extent. The readiness with which
eel serum parts with its lethal properties, and the restricted
conditions under which they can operate, sufficiently assure us that
in the present state of our knowledge there is no danger to be
apprehended from this fish, and in the absence of any experiments to
show what is the effect on human beings of subcutaneous inoculations
of such blood, there is no call for this substance to be scheduled
under the Poisons Act. We have, however, by no means exhausted the
extremely curious properties which characterise this material, and
these properties are brought to light in a remarkable manner in
connection with the investigations which have been carried out to
artificially protect animals from its lethal influence, and also in
some interesting experiments which have been made to compare the
toxicity of eel blood with that of vipers.
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