Post-mortem showed dural vessels of cord and brain full of blood. Stomach pinker than normal: mesenteric vessels dilated. Heart almost empty of blood. Kidneys congested. =SUMMARY OF FEEDING EXPERIMENTS ON RABBITS.= These experiments indicate that an acute form of poisoning may be induced by feeding concentrated aqueous extracts of _Astragalus mollissimus_ and _Aragallus lamberti_ from Hugo, Colo., and Imperial, Nebr., to rabbits, and that if the extract is given in smaller and repeated doses a more prolonged or chronic condition may follow. The rabbits showing the chronic effects of these plants exhibit symptoms which have a marked parallelism with those reported as occurring in larger herbivora (horses and cattle) on the range when locoed; that is, the loss of appetite (Experiment No. 9), the emaciation and loss in weight (Experiment No. 9), the dullness and stupor, with more or less anesthesia (Experiment No. 7), the disturbance in the visual function (Experiment No. 9), and the mental symptoms (Experiment No. 6). The occasional abortion compares with what has been observed in larger animals. The dried _Astragalus mollissimus_ and _Aragallus lamberti_ still retained their poisonous properties, as we were able to kill with aqueous extracts of the dried plants made in the laboratory under the proper conditions. =EXPERIMENTS ON SHEEP.= _Experiment No. 1._--On May 31, 1906, a sheep weighing 32.2 kilos was fed with a concentrated aqueous extract of 1,000 grams of the fresh _Astragalus mollissimus_ preserved in chloroform water. The temperature at 11 o'clock, the time of feeding, was 103.4°F. At 11.45 a.m. this dose was repeated. At 12 o'clock the temperature was 104.1°F. At 12.45 the animal urinated. At 1.10 p.m. a similar extract of 2,000 grams was fed. The total liquid used was 1,500 c.c. On June 1 no symptoms were noted. On June 5 an extract of 3,000 grams of fresh _Aragallus lamberti_ and 3,000 grams of _Astragalus mollissimus_ was fed. After feeding this the animal could be easily turned over on its back and its ear pricked with impunity. The animal at this time weighed 30.8 kilos. On June 6, at 11 a.m., the temperature was 104°F. The sheep had numerous soft stools, and was very dull, and would not eat. On June 7 the temperature was 103.7°F. and the sheep still refused to eat. On the 8th the temperature was 103.2°F. at 10.40 a.m., and the stools were still numerous and soft. There were then fed 640 c.c., representing the aqueous extract of 4,000 grams of the fresh _Aragallus lamberti_. The animal could be easily turned on its back. It weighed at this time 28.57 kilos. On June 9, at 10.47 a.m., the temperature was 103.4°F. The sheep still did not eat, but had no diarrhea. It now weighed 27.9 kilos, and the temperature was 103°F. at 10.45 a.m.