The acetic acid extract of the ash of 125 grams of a mixture of the dried _Astragalus mollissimus_ and _Aragallus lamberti_ received from Hugo, Colo., June, 1907, after freeing from acid, was fed to a rabbit weighing 1,304 grams on July 29. On July 30 it weighed 1,332.4 grams. August 1 it weighed 1,219 grams, and it died the same day. The stomach was reddened and showed ulcers. A similar extract from 250 grams of the same dried plants on boiling gave a heavy precipitate, but this precipitate was inactive, while the filtrate killed a rabbit in four hours. Of dry _Aragallus lamberti_ collected in September, 1906, 200 grams were extracted with water and fed to a rabbit weighing 1,516.7 grams. Two days later the animal weighed 1,360 grams and died the same day. The ash from 200 grams of the same dried plant was extracted with acetic acid, and after evaporating off the acid this was fed to a rabbit weighing 2,045.3 grams. Seven days later the animal weighed 1,729.3 grams, having lost 316 grams in weight. The ash from 250 grams of the same species of plant, after similar treatment with acetic acid, induced death in a rabbit weighing 2,069 grams in 2 hours and 20 minutes. The stomach was inflamed. * * * * * FOOTNOTES: [158] Work is now being done by the writer on the inorganic constituents of various plants. [159] Scattered throughout the veterinary literature one finds cases of poisoning in animals with symptoms similar to those occurring in locoed animals which are attributed to eating plants grown on a peculiar soil, as in Oserow, Ueber Krankh. d. Pferde, welche Aehnlichkeit mit der Cerebro-spinal meningitis haben, aber durch Vergiftungen mit Gräsern von Salzgründen (Salzmooren) verursacht werden, Journ. f. Allgem. Veterinär-Medicin, St. Petersburg, p. 486, 1906. Abstract in Jahresber. über d. Leistungen auf dem Gebiete d. Veterinär-Medicin, vol. 26, p. 226, 1906.--Compare also Étude sur Quelques Plantes Vénéneuses des Regions Calcaires, Bul. Soc. Cent. de Méd. Vét., vol. 48, p. 378. 1894. [160] After completing this work the writer found that Sayre had said that he "had the suggestion that the harm coming from this plant is due to the inorganic constituents; this clue has been followed up, but like the others has brought us no nearer to the solution of the problem." Kans. Acad. Sci. Trans., vol. 18, p. 144. 1903. =EFFECT OF THE AQUEOUS EXTRACT OF ASHED LOCO PLANTS.= The filtrate from the ash from 200 grams of dried _Astragalus mollissimus_, from Imperial, Nebr., after similar treatment with acetic acid water and freed from free acid, killed a rabbit in several hours.