Loco-acid, body supposed to be in loco plants, 30 disease, attributed to hairs on plants, 22, 28 worms, 31, 34 experiments, Colorado, results, 5 symptoms, descriptions, 11, 12-16, 17, 24, 26, 28, 29, 33, 36-44 eating habit, description, 14, 15 intoxication, 13, 16, 21, 22 investigations from a pharmacological standpoint, historical sketch, 19-34 plants, ash determinations, 54-55 ashed, aqueous extracts, effect, 48-52 barium determinations, 55-57 eaten with large amounts of other food presumably not dangerous, 71 effects on human beings, 15, 20, 22, 35 extracts, digestion with pepsin and pancreatin, experiments, 66-68 extracts, variations in toxicity, 66-71 use in laboratory experiments, varying toxicity, 36-52, 66-71 list, 10 poison, varying in carnivorous and herbivorous animals, 23 with season, variety, and origin, 25, 48 uses as food, forage, medicine, etc., 35 without barium not poisonous, 68-71 _See also_ Loco weeds. poison, attempts to isolate the active principle, 47 poisoning, laboratory study, results, 5-6 symptoms, 11, 12-16, 17, 24, 26, 28, 29, 33, 36-44 reproduction in rabbits, 29, 33, 36-44, 75 theoretical antidote, 71-72 Locoed animals, clinical symptoms, 12-16 pathological conditions as described on the range, 18-19 derivation of term, 9 Locoin, experiments by Ruedi, 30 Loco-weed disease, geographical distribution, 9 family, notes on use of various members, 35 _See also_ Loco plants. Lopes, A., reference to work, 64 Lotus americanus, supposed cause of loco disease, 10