A very interesting human case cited by Forel on the authority of Schweighofer is that of a normal woman who had three sound children when married to a normal man. After the death of this husband she married an inebriate by whom she had three other children. One of these suffered from infantilism, one turned out to be a drunkard, and the third became a social degenerate and drunkard. Moreover the first two contracted tuberculosis, although hitherto the family stock had been free from this malady. Ultimately the woman married again and by this third husband, who was normal, she again had sound children. Similar cases might be cited, as, for example, a record of eighty-three epileptics, of whom sixty had drunken parents, but it can be urged against all of them, of course, that the defective offspring were due to an innate degeneracy of the drunken parent which made him a drunkard rather than to the effects of the alcohol he took. While one is skeptical as to the validity of this objection in all of the many cases which occur with such monotonous frequency in man, there is no way of escaping such an interpretation with the evidence at hand. It must be admitted, moreover, that there are many families with one or both parents alcoholic in which the children are not mentally defective. =Experimental Alcoholism in Lower Animals.--=Many of the objections that exist in the case of man, however, do not apply in that of lower animals. If normal animals are experimentally alcoholized and are shown to produce defective offspring under such conditions, then in their cases at least, the disorders in the offspring must be due to the effects of alcohol and not to an innately degenerate condition of the parent. Disorders similar to some of those seen in the children of alcoholics do actually result in alcoholized animals of one kind or another. Against the earlier experiments on animals it has been urged that too few individuals were used to give conclusive results, but this objection can not be brought against the recent experiments of Stockard. While he has published accounts of his work in various scientific periodicals lately, the reader will find a full statement of his own experiments, together with a review of the whole subject of experimental alcoholism in animals and the effects on progeny in _The American Naturalist_, Vol. XLVII, November, 1913, together with a useful bibliography. Before taking up Stockard's results we may select a few of the more significant experiments made earlier by other investigators.