Lines four and five give a comparison between the 103 total matings of all treated individuals and 35 normal matings. In the first case almost 42 per cent. of the matings gave negative results or early abortions, whereas in the normal control matings, failure to yield a full-term litter occurred in only two cases. The 103 matings of alcoholic animals gave only 46 living litters, or about 45 per cent. On the other hand the 35 control matings produced 32 living litters, or 91-1/2 per cent. It will be observed also that from such of the 103 matings of alcoholics as produced young there were 30 still-born, 37 which died soon after birth, and only 52 surviving young, whereas from the 35 matings of normal individuals there were only 4 still-born young, 4 which died soon after birth, and 56 surviving young. The bottom line of the table, although, as Stockard points out, containing too few cases to prove wholly convincing, indicates that alcoholizing erstwhile normal females during pregnancy was not particularly harmful to the embryos _in utero_. Some of the most interesting results were obtained when offspring termed second generation animals, derived from alcoholic parents though not themselves treated with alcohol, were mated in various ways. When such individuals were mated with normal individuals, although the litters were small, the results were normal, the normal mate having seemingly counteracted any defects which might have lurked in the second generation animal. On the other hand, out of three matings of second generation animals with alcoholic individuals, two produced still-born young, of which one was markedly deformed, while the third yielded two living young. However, the most striking results were obtained when two second generation individuals, the offspring of alcoholic parents, were bred together. Although themselves untreated, these individuals, of which 19 matings were made, produced as many or more defective young than did their alcoholic parents. Seven of the matings were unfruitful. The remaining 12 matings gave living litters consisting of 19 individuals in all. Six of these showed various nerve disorders (spasms, epileptic-like seizures, etc.) soon after birth; one was eyeless and otherwise deformed.