The Pasteur Institute.--The time had now come for the establishment of an institute, not alone for the treatment of hydrophobia, but also for the scientific study of means to control other diseases, as diphtheria, typhoid, tuberculosis, etc. A movement was set on foot for a popular subscription to meet this need. The response to this call on the part of the common people was gratifying. "The extraordinary enthusiasm which accompanied the foundation of this great institution has certainly not been equaled in our time. Considerable sums of money were subscribed in foreign countries, while contributions poured in from every part of France. Even the inhabitants of obscure little towns and villages organized fêtes, and clubbed together to send their small gifts" (Franckland). The total sum subscribed on the date of the opening ceremony amounted to 3,586,680 francs. The institute was formally opened on November 14th, 1888, with impressive ceremonies presided over by the President of the Republic of France. The establishment of this institute was an event of great scientific importance. Here, within the first decade of its existence, were successfully treated more than twenty thousand cases of hydrophobia. Here has been discovered by Roux the antitoxin for diphtheria, and here have been established the principles of inoculation against the bubonic plague, against lockjaw, against tuberculosis and other maladies, and of the recent microbe inoculations of Wright of London. More than thirty "Pasteur institutes," with aims similar to the parent institution, have been established in different parts of the civilized world. Pasteur died in 1895, greatly honored by the whole world. On Saturday, October 5th of that year, a national funeral was conducted in the Church of Notre-Dame, which was attended by the representatives of the state and of numerous scientific bodies and learned societies. Koch.--Robert Koch (Fig. 93) was born in 1843, and is still living, engaged actively in work in the University of Berlin. His studies have been mainly those of a medical man, and have been crowned with remarkable success. In 1881 he discovered the germ of tuberculosis, in 1883 the germ that produces Asiatic cholera, and since that time his name has been connected with a number of remarkable discoveries that are of continuous practical application in the science of medicine. [Illustration: Fig. 93.--Robert Koch, Born 1843.]