Heredity, blood groups in relation to, 86, 87, 90, 91 Mendelian theory of, 86, 90 Higginson’s transfusion instrument, 13, 14 Hirudin, use of, 16 Histamine, 30 production of, 30 production of shock by, 30 Horse asthma, transmission of, 68 Howard’s method of transfusion of infants, 135 Hydrogen-ion concentration in the blood, 28, 31 shock in relation to, 28, 32 Hydrophobia, transfusion for, 9 Immunized blood, transfusion by, in pyogenic infections, 58 Incompatibility, symptoms of, 6, 75 Indirect transfusion, 111 Infants, blood groups in, 84, 92 compared with those of mothers, 86, 92 blood reactions in, 84, 90, 92 transfusion of, 48 conditions necessitating, 49, 134 dosage, 136 technique, 134-136 with maternal blood, 85, 92 withdrawal of blood from, 136 Influenzal pneumonia, transfusion for, 61 Innocent VIII, 2 Internal saphenous vein, injection of blood into, in infants, 135 Iso-agglutinins, 72, 79 distribution among animals, 79, 80 Iso-hæmolysins, 72, 79 in animals, artificial reproduction of, 96 Isotonic saline solution in treatment of shock, 34 Jaundice, 44 acholuric, transfusion in, 94 blood groups in patients with, 93 hæmorrhage following operation in cases of, 44 transfusion in cases of, 44 Joekes, Dr., 52, 57 Jugular vein, injection of blood into, 135 Keith, on blood volume changes, 24, 27 on shock and hæmorrhage, 32 Kimpton and Brown, improvements in technique of transfusion by, 16 Kimpton-Brown tube, whole blood transfusion with, technique, 114 King, Edmund, transfusion experiments by, 3, 4, 8 Lamb’s blood, early transfusions with, 5, 9, 15 Legitimacy, inheritance of blood groups in relation to, 92 Leukæmia, 50 blood groups in patients suffering from, 81 Lewisohn’s sodium citrate experiments, 16, 120, 122, 123 Longitudinal sinus, use of, 135 Lower, Richard, transfusion experiments by, 3, 8 Malaria, transmission by transfusion, 67, 68 Malignant disease, blood groups in patients suffering from, 81, 93 “Maternal threat,” 85, 92 Measles, blood injections in, 62 Median basilic vein, accessible for direct transfusion, 108 incision of, 130 puncture of, 126-128 Melæna neonatorum, transfusion for, technique, 134, 135 value of transfusion in, 48 Mendelian theory, 86, 90 of blood groups, 86, 87, 88, 90 Milk, injection of, 15 maternal, agglutinins in, 86 Muscle, damaged, production of histamine from, 30 Needle, for transfusion, 126 case of, 126 improved form of, 113 Nephritis, transfusion treatment of, 63 New-born infants, blood donors for, 49 blood reactions of, 84, 90, 92 hæmorrhagic disease of, 48, 49 transfusion of, 48 technique, 134-136 with maternal blood, 84, 85, 92 Nitrobenzol poisoning, transfusion treatment of, 65 Obstetrics, transfusion in, 42