Quite different in its effects has been the drug which has been extracted from this plant, known as _Erythroxylon Coca_. Far from being a beneficial and harmless stimulant, cocaine is now one of the drug evils of our time. Its use, outside that prescribed by physicians, is forbidden practically everywhere, but its consumption in this country, aside from its great and legitimate use as a relief from pain, is still very large. The number of drug plants is legion, so large in fact, that volumes have been filled with descriptions and notes about them. A few of the most important, omitting those already mentioned, are listed below: DRUG DERIVED FROM THE NATIVE Betel nut. Seed of Areca Catechu. India. Calamus. Rootstock of Acorus Calamus. Eastern U. S. and in Asia. Sarsaparilla. Roots of various species of Tropical America. Smilax. Saffron. Stigmas of Crocus sativus. Europe. Arrowroot. Rootstock of Maranta arundinacea. Tropical America. Cubeb. Unripe fruit of Piper Cubeba. Old World tropics. Creosote. Wood of Fagus americana North America and and F. sylvatica. Europe. Hydrastis. Rootstock of Hydrastis canadensis. Eastern N. America. Star Anise. Fruit of Illicium anisatum. Southern China. Camphor. All parts of Cinnamomum China and Japan. Camphora. Witch-hazel. Leaves and bark of Hamamelis Eastern N. America. virginiana. Licorice. Underground parts of Glycyrrhiza Europe. glabra. Cascara Bark of Rhamnus Purshianus. Western United Sagrada. States. Ginseng. Rootstock of Panax quinquefolium. Eastern N. America and Asia. Wintergreen. Leaves of Gaultheria procumbens. Eastern N. America. Nux vomica. Seeds of Strychnos Nux India. vomica. Digitalis. Leaves of Digitalis purpurea. Europe. Ipecac. Root of Uragoga Ipecacuanha. Brazil. Castor oil. Seeds of Ricinus communis. Africa or India. 6. THE STORY OF TOBACCO