The importance of the settlements he founded was soon apparent; and in 1620 they were formed into a government independent of that of Paraguay, under the name of the Government of La Plata; it comprised all south of the junction of the rivers Paranã and Paraguay. Santa Fé in consequence became a dependency of Buenos Ayres; an arrangement confirmed in every territorial settlement subsequently made by any competent authority. In the domestic dissensions, however, which succeeded the establishment of the Independent Government at Buenos Ayres, Santa Fé took an active part, and disputed the right of the newly-constituted authorities to interfere in the nomination of the provincial administrations. Under these circumstances, in 1818, Lopez, a military officer who had particularly distinguished himself in his resistance to the Central Government upon this point, obtained the command of the province, in which he has ever since been continued. Various circumstances have concurred to leave him not only in undisturbed possession of this local authority, but to render him in later times a personage of some importance in the political history of the Republic. The jurisdiction he lays claim to for the soi-disant province of Santa Fé extends as far south as the Arroyo del Medio, to the west to the lakes of Porongos, and to the north as far as the lands of the Indians of the Gran-chaco, or Great Desert, against whom he has enough to do to defend himself. In old times Santa Fé under the protection of the Central Government, which spared no expense in constructing forts and maintaining the forces requisite to keep the Indians in check, was the central point of communication not only between Buenos Ayres and Paraguay, but between Paraguay and the provinces of Cuyo and Tucuman: the wines and dried fruits of Mendoza and St. Juan were brought there to be carried up to Corrientes and Paraguay, which in return supplied the people of those provinces, as well as those of Chile and Peru, through the same channel, with all the yerba-maté they required, of which the annual consumption in those provinces alone was calculated at from 3,000,000 to 4,000,000 lbs. The _estancieros_ were amongst the richest in the Vice-Royalty; and their cattle-farms not only covered the territory of Santa Fé, but large tracts on the eastern shores of the river in the Entre Rios; from which they furnished by far the greater part of the 50,000 mules yearly sent to Salta for the service of Peru. Their situation is now a very different one: the stoppage of the trade with Paraguay and Peru has reduced them to a wretched state of poverty; and their estrangement from the capital having left them without adequate means of defence, the savages have attacked them with impunity, laid waste the greater part of the province, and more than once threatened the town itself with annihilation.