Until the year 360, when the church of S. Sophia was opened to public worship by the Emperor Constantius, S. Irene appears to have been the cathedral of the city. Hence, probably, the name sometimes given to it, the Patriarchate, [Greek: to patriarcheion].[123] Nor did the church lose its primacy altogether even after the erection of S. Sophia. On the contrary, the two churches were regarded as forming one sanctuary; they were enclosed within the same court, served by the same clergy, and known by the same name, 'the Great Church,' [Greek: hê Megalê Ekklêsia].[124] S. Irene was again the sole cathedral building, while S. Sophia lay in ruins for eleven years after being set on fire in 404, on the occasion of the final banishment of John Chrysostom. S. Irene comes prominently into view during the fierce struggle between the adherents of the Nicene Creed and the Arians, in the half-century which followed the inauguration of New Rome. Having been persuaded that the point at issue between the two theological parties was not essential, and that the agitation of the question was due to love of disputation, Constantine the Great, who valued peace at almost any price, attempted to suppress the controversy by his authority, and accordingly ordered the Patriarch Alexander to admit Arius, then present in the city, to the Holy Communion. With this order Alexander, a champion of the Nicene Creed, refused to comply. Whereupon the followers of Arius decided to have recourse to violence. But on the very eve of the day fixed to carry out their purpose, Arius was taken suddenly ill in the Forum of Constantine and died on the spot. The historian Socrates regards the event as the act of God, for when the patriarch heard what the heretics intended to do, he retired to the church of S. Irene, and there for many days and nights, with fasting and tears, and with his lips pressed to the altar, implored divine succour in his terrible extremity. 'If the opinions of Arius be true,' the patriarch prayed, 'let me die; but if they are false let him be judged.' The tragic end of Arius was considered the answer to that prayer.