Why is it that members of the medical profession should take an exceptional interest in poisonous reptiles? Professor Reichert and Dr. S. Weir Mitchell spent a large portion of their leisure hours for several years in experimenting with the virus of rattlesnakes, and of the Gila monster, without, however, quite exhausting the subject. Doctor Holmes kept a rattlesnake in a cage for a pet, and was accustomed to stir it up with an ox-goad. A New York doctor lost his life by fooling with a poisonous snake, and another in Liverpool frightened a whole congregation of scientists with two torpid rattlesnakes which suddenly came to life on the president's table. Does it arise from their custom of dealing with deadly poisons, or is it because they officiate as the high priests of mortality? Doctor Holmes's "Elsie Venner" was one of the offshoots of this peculiar medical interest, and when we think of it in that light the story seems natural enough. The idea of a snaky woman is as old as the fable of Medusa. I read the novel when I was fifteen, and it made as decided an impression on me as "Ivanhoe" or "Pickwick." I remember especially a proverbial saying of the old doctor who serves as the presiding genius of the plot: he knew "the kind of people who are never sick but what they are going to die, and the other kind who never know they are sick until they are dead." If Doctor Holmes had taken this as his text, and written a novel on those lines, he might have created a work of far-reaching importance. He appears to have known very little concerning poisonous reptiles; had never heard of the terrible fer-de-lance, which infests the cane-swamps of Brazil--a snake ten feet in length which strikes without warning and straight as a fencer's thrust. But "Elsie Venner" and Holmes's second novel, "The Guardian Angel," are, to use Lowell's expression on a different subject: "As full of wit, gumption and good Yankee sense, As there are mosses on an old stone fence." In the autumn of 1865 some Harvard students, radically inclined, obtained possession of a religious society in the college called the Christian Union, revolutionized it and changed its name to the Liberal Fraternity. They then invited Emerson, Henry James, Sr., Doctor Holmes, and Colonel Higginson to deliver lectures in Cambridge under their auspices. This was a pretty bold stroke, but Holmes evidently liked it. He said to the committee that waited upon him: "What is your rank and file? How deep do you go down into the class?" He also promised to lecture, and that he did not was more the fault of the students than his own. He was by no means a radical in religious matters, but he hated small sectarian differences-- the substitution of dogma for true religious feeling. In his poem at the grand Harvard celebration in 1886 he made a special point of this principle: "For nothing burns with such amazing speed As the dry sticks of a religious creed."