Iron is a very important element in the treatment of these patients, though sometimes it will be found difficult to have it rightly taken and properly assimilated. I have come to use largely the pyrophosphate of iron in powder, in five grain capsules after meals, in conjunction with the mixture referred to, half an hour before meals. Sometimes dialyzed iron, half to one teaspoonful in water, taken in the middle of the meal, acts best, though I prefer the pyrophosphate, as phosphorus in some form should always be given for some time to these patients; it is to be remembered that the iron, potassium and other elements of the blood cells are united as phosphates. Occasionally I have to give the acetate of potassium with nux vomica and infusion of quassia after meals, in place of the other mixture, which after a while may be distasteful. But remember that potassium is the sheet anchor, and also that in some way the solids in the urine must be kept up to the standard of health, as I mentioned in a former lecture, which I occasionally accomplish by adding sweet spirits of nitre, etc. I have emphasized imperfect intestinal action as a most important element in the probable causation of cancer, and the regulation of this function will often require the very greatest care, patience, and often even ingenuity on the part of the physician. The stools should really be frequently inspected. It is not enough to inquire at each visit if the “bowels are regular,” but the matter must be patiently investigated, as to the character, quantity, color, odor, hour of defecation, which should be after breakfast, etc. Nor is it enough just to order purgatives or laxatives from time to time, but such attention should be given, and such remedies and measures applied, as will secure the best possible performance of this most important function. The mixture just spoken of, altered as required in regard to its cascara content, will often suffice, but many of my patients also secure a full and free intestinal relief each week, by means of the old pills which you hear me order so often in this clinic: ℞ Massæ hydrargyri, Extr. Colocynth. Comp. āā gr. x, Pulv. Ipecac. gr. ii. M. Div. in capsules No. IV. Take 2 at bedtime and 2 the second night after. I also use greatly the excellent combination of ℞ Podophyllin, Cascarin, Aloin, āā gr. ¼, M. one or more of these at bedtime, as needed. I do not approve of mineral waters or saline laxatives in these cases, nor of mineral oil, and never employ enemata, except for emergencies.