In November 1861, the author was called to perform this operation upon the short-horn Galloway cow, Josephine the Second, belonging to Henry Ingersoll, Esq., of this city. This cow was born May 8th, 1860. The morning was cold and cloudy. About ten o'clock the cow was cast, with the assistance of R. McClure, V.S., after which she was placed under the influence of chloric ether. He then made an incision, about five inches in length, through the skin and walls of the abdomen, midway between the pelvis bone and the last rib on the left side, passing in his right hand, cutting away the ovaries from the Fallopian tubes with the thumbnail. The opening on the side was then closed by means of the interrupted suture. The animal recovered from the influence of the anaesthetic in about fifteen minutes, when she was allowed to rise, and walk back to her stall. Upon the morning of the second day succeeding the operation, the animal was visited and found to be in good spirits, apparently suffering very little pain or inconvenience from the operation, and the wound healing nicely. Since that time, he has operated upon some twenty cows, all of which, with a single exception, have thus far proved satisfactory. Several of these cows are under the direction of a committee from the Philadelphia Society for promoting Agriculture, whose duty it is to have a daily record kept of each cow's yield of butter and milk, for one year from the time of spaying. Their report will be perused by the agricultural community with much interest. The author's own experience will not justify him in speaking either in favor of, or against, this operation; as sufficient time has not as yet elapsed to satisfy him as to its relative advantages and disadvantages. He, however, regards the operation as comparatively safe. The French estimate the loss at about fifteen per cent., and the gain at thirty per cent. Of those upon which he has operated, not a single animal died. A LIST OF MEDICINES USED IN TREATING CATTLE. The medicines used in the treatment of the diseases of cattle, are essentially the same as those in vogue for the diseases of the human being and the horse,--the only difference being in their combination and the quantities administered. ABSORBENTS.--Medicines which destroy acidities in the stomach and bowels; such as chalk, magnesia, etc. ALTERATIVES.--Medicines which restore the healthy functions of secretion, by gradually changing the morbid action in an impaired constitution. Those in most common use are AEthiops mineral, antimony, rosin, sulphur, etc., which form the principal ingredients in all condition-powders, and are chiefly useful in diseases of the skin, such as hide-bound, mange, surfeit, etc. ALTERATIVE POWDER.--Sulphur pulverized, one pound; black antimony, one half a pound; nitrate of potassa, four ounces; sulphate of iron, one half a pound; linseed meal, one pound; mix well; dose, one half an ounce, night and morning.