Nouffer was a surgeon living at Morat, in Switzerland. He had practised his special worm cure treatment for many years, and by it he had acquired a considerable local fame. After his death his widow, who knew all about the secret, continued to receive patients. Among those who came to her was a Russian, Prince Baryantinski, who was staying in the neighbourhood and had heard of the cure. He had been troubled for years with tapeworm, and Madame Nouffer’s remedy cured him. The Prince reported the facts to his regular physician at Paris, and consequently cases were sent from that city to the Swiss lady. She was so successful that the king was induced to give her the sum named for the revelation of her method, which was briefly as follows:-- For a day or two the patient was fed on buttered toast only. Meanwhile enemas of mallow and marshmallow with a little salt and olive oil were administered. Then, early in the morning, 3 drachms of powder of male fern in a teacupful of water was taken. Candied lemon was chewed after the dose to relieve the nauseousness, and the mouth was washed out with an aromatic water. If the patient vomited the medicine another dose was given. Two hours after the male fern a bolus containing 12 grains each of calomel and resin of scammony, with 5 grains of gamboge, and with confection of hyacinth as the excipient, had to be taken. A cup of warm tea was recommended shortly after the bolus. The doses quoted were regarded as average ones. They might be modified according to the strength of the patient. Generally the treatment narrated sufficed to expel the worm. If it did not, the whole proceeding was repeated. Male fern was a remedy mentioned by Dioscorides and other ancient writers, but it had been forgotten for centuries until Madame Nouffer’s system brought it to the recollection of medical practitioners. It again fell out of use, but a French physician named Jobert revived its popularity in 1869. He was assisted in the preparation of the remedy by Mr. Hepp, pharmacien of the Civil Hospital of Strasburg. _Bestucheff’s Tincture and La Mothe’s Golden Drops._