Chronicles of Pharmacy, Vol. 1 (of 2)Wootton, A. C.
History
Chronicles of Pharmacy, Vol. 1 (of 2)
Wootton, A. C.
Pharmacy -- History
Ether is alcohol, two molecules deprived of H_{2}O [alcohol,
C_{2}H_{5}O HO; ether, (C_{2}H_{5})_{2}O]. Distilling spirit of wine
and sulphuric acid together, it seemed obvious that the sulphuric
acid should possess itself of the H_{2}O, and leave the ether. But on
this theory it was not possible to explain the invariable formation
of sulphovinic acid (a sulphate of ethyl) in the process, nor the
simultaneous distillation of water with the ether. Williamson proved
that the acid first combined with the alcohol molecule, setting
the water free, and that then an excess of alcohol decomposed the
sulphovinic acid thus formed into free sulphuric acid and ether, this
circuit proceeding continuously.
SPIRIT OF NITROUS ETHER.
This popular medicine has been traced back to Raymond Lully in the
thirteenth century, and to Basil Valentine. But the doctor who brought
it into general use was Sylvius (de la Boe) of Leyden, for whom it was
sold as a lithontryptic at a very high price. It first appeared in
the P.L., 1746, as Spiritus Nitri dulcis. In English this was for a
long time called “dulcified spirit of nitre,” and in the form of sweet
spirit of nitre still remains on our labels. In the P.L., 1788, the
title was changed to Spiritus Ætheris nitrosi, and in that of 1809 to
Spiritus Ætheris nitrici. The process ordered in the first official
formula was to distil 6 oz. (apoth. weight) of nitric acid of 1·5
specific gravity, with 32 fluid oz. of rectified spirit. Successive
reductions were made in the proportion and strength of the acid in the
pharmacopœias of 1809, 1824, and 1851, to 3½ fluid ounces of nitric
acid, sp. gr. 1·42, with 40 fluid ounces of rectified spirit, and a
product of 28 fluid ounces. The object of these several modifications
was to avoid the violent reaction which affected the nature of the
product.
ETHIOPS.
Æthiops or Ethiops originally meant a negro or something black. The
word is alleged to have been derived from aithein, to burn, and ops,
the face, but this etymology was probably devised to fit the facts.
There is no historical evidence in its favour. Most likely the word
was a native African one of unknown meaning. It became a popular
pharmaceutical term two or three hundred years ago, but is now almost
obsolete, at least in this country. In France several mercurial
preparations are still known by the name of Ethiops. There are, for
instance, the Ethiops magnesium, the Ethiops saccharine, and the
Ethiops gommeux; combinations of mercury with magnesia, sugar, and gum
acacia respectively. These designations echo the mysteries of alchemy.
Public-domain text, read in full here on John Shaqi.
Reviews
Reviews
No reviews yet
Be the first to share your thoughts on this work.
Elsewhere in the archive
Join the Discussion
Join the discussion
Sign in to leave a comment or review.
Sign InorCreate an account