Chronicles of Pharmacy, Vol. 1 (of 2)Wootton, A. C.
History
Chronicles of Pharmacy, Vol. 1 (of 2)
Wootton, A. C.
Pharmacy -- History
The hypophosphites in the form of syrup were introduced by Dr. J. F.
Churchill, of Paris, as specifics in consumptive diseases about 1857.
His preference of these salts over the phosphates was based on the
theory that the deficiency in the system in a phthisical condition
was not of phosphates, which had been completely oxidised, but of
a phosphide in an oxidisable condition, and this requirement was
fulfilled by the hypophosphites. The latter he compared to wood or
coal, the phosphates to ashes, so far as active energy was concerned.
Dr. Churchill’s interest in a special manufacture of the hypophosphite
syrups prejudiced the medical profession against his theories, and it
is not certain that he got a fair hearing in consequence. The general
verdict was that his results were not obtained by other experimenters,
but for a good many years past syrups of the hypophosphites have been
among the most popular of our general tonics.
Phosphorus is soluble in alcohol, ether, chloroform, bisulphide of
carbon, and to a very small extent in water.
* * * * *
Phosphor paste as a vermin killer was ordered by the Prussian
Government to be substituted for arsenical compounds in 1843, and it is
probable that to some degree the alteration has been successful, though
in France it was found that phosphorus in this form became a popular
agent for suicide and criminal poisoning.
SAL PRUNELLA
was at one time in high esteem, as it was believed that by the process
adopted for making it the nitre was specially purified. Purified nitre
was melted in an iron pot and a little flowers of sulphur (1 oz. to 2
lb.) was sprinkled on it, a little at a time. The sulphur deflagrating
was supposed to exercise the purifying influence on the nitre. The
actual effect was to convert a small part of the nitrate of potash into
sulphate. It was first called Sal Prunella in Germany from the belief
that it was a specific against a certain plum-coloured quinsy of an
epidemic character. Boerhaave advised the omission of the sulphur, but
believed that melting the pure nitre and moulding it was of medicinal
value by evaporating aqueous moisture.
Nitre and flowers of sulphur were deflagrated together before the Sal
Prunella theory was invented, equal quantities being employed. The
resulting combination, which was of course sulphate of potash, was
known as Sal Polychrestum, the Salt of Many Virtues.
SAL GEMMÆ.
Sal Gemmæ or Sal Fossile was the name given to rock salt, particularly
to the transparent and the tinted varieties. It was believed to be more
penetrating than the salt derived from sea water, and this property
Lemery ascribed to the circumstance that it had never been dissolved in
water, and therefore retained all its native keenness.
SPIRIT OF SALT.
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