Liquor Bismuthi et Ammonii Citratis was introduced into the B.P. 1867, as an imitation of the proprietary Liquor Bismuthi, which Mr. G. F. Schacht, pharmaceutical chemist, of Clifton, had invented a few years previously. It was found that the official preparation differed from the proprietary one in taste and action principally because no attempt had been made to free it from the nitric acid used to dissolve the bismuth. This was corrected in 1885 by a liquor prepared from citrate of bismuth dissolved by solution of ammonia. This method has been further elaborated. Continental physicians have not favoured a solution of bismuth. They consider that the remedial value of bismuth depends on its insolubility; this view now obtains in England also. Trochisci Bismuthi Compositi of the B.P. 1864, were believed to be intended to imitate the “Heartburn Tablets,” made by Dr. Burt, an eminent medical practitioner of Edinburgh in the early part of the nineteenth century, and sold for him at a guinea a pound. Notwithstanding the price, perhaps because of it, these tablets attained to considerable popularity. It was said that Dr. Burt and his apprentices made all he supplied in his kitchen. Some said that his tablets contained no bismuth, the antacid properties being due entirely to chalk. In 1867 rose-flavour was substituted for cinnamon in the official lozenges, and in 1898 the oxynitrate of bismuth gave place to oxycarbonate. GOLD. For gold in physick is a cordiall, Therefore he loved gold in special. Chaucer’s _Doctour of Phisike_. The employment of gold as a remedy is but rarely mentioned in ancient medical literature. Gold leaf was probably used by the Egyptians to cover abrasions of the skin. Pieces of it have been found on mummies apparently so applied. Some of the Arab alchemists, Geber among them, are believed to have made some kind of elixir of life from gold, but their writings are too enigmatical to be trusted. Avicenna mentions gold among blood purifiers, and the gilding of pills originated with the Eastern pharmacists. Probably it was believed that the gold added to the efficacy of the pills. It was not, however, until the period of chemical medicine in Europe that gold attained its special fame. Arnold of Villa Nova, and Raymond Lully were among the advocates of the medicinal virtues of gold; but in the century before Paracelsus appeared, Brassavolus, Fallopius, and other writers questioned its virtues. With Paracelsus, Quercetanus, Libavius, Crollius, and others of that age, however, gold entered fully into its kingdom. They could hardly exalt it too highly. But it is difficult to ascertain from the writings of this period what the chemical physicians understood by gold.