Francis Anthony was a famous quack in the reigns of Queen Elizabeth and James I. The College of Physicians took proceedings against him several times, fined him and imprisoned him, but aristocratic influences were exerted on his behalf and ultimately the College found it prudent to let him alone. His panacea “Aurum potabile” professed to be a solution of gold, and the wealthy classes of the period had unbounded belief in its wonderful remedial virtues. Some years after the death of Anthony the famous Honourable Robert Boyle (the “Father of philosophy and brother of the Earl of Cork”) in the “Sceptical Chymist” wrote that though he was prejudiced against all such compositions, he had known (and he describes) some such wonderful cures resulting from this aurum potabile that he was compelled to bear testimony to its efficacy. Boyle also states that he had seen in part the preparation of this nostrum. He rather enigmatically reports that there was but a single ingredient associated with the gold, that this came from above, and was reputed to be one of the simplest substances in nature. * * * * * Anthony claimed that his product would cure most diseases; vomitings, fluxes, stoppages, fevers, plague, and palsies were included among the evils which it overcame. Several of the well-known physicians of the time wrote angry pamphlets denouncing Anthony’s pretensions. Dr. Matthew Gwynne’s “Aurum non aurum,” and Dr. Cotta’s “Cotta contra Antonium” were two of the most noted. Of course these gave Anthony opportunities of reply, and largely promoted the business. In one of his later publications Anthony boldly offered to exhibit his process to a committee of proper and unbiassed witnesses with the object of proving that the compound was truly a solution of gold. The challenge appears to have been accepted, and the Master of the Mint, Baron Thomas Knivet, and other experts were present when the test was made. According to Gwynne the result was failure, but I do not find any unprejudiced report of the experiment. The writer of the life of Anthony in the old “Biographia Britannica,” who is his warm partisan, gives what he declares to have been the genuine formula for the aurum potabile. It had long been in the possession of Anthony’s descendants, he says, and was given to him (the author of the biography) by an eminent chemist. If this is true it is evident that a solution of gold would not have resulted from the process.