A curious controversy prevailed for a long time among the chemical and medical authorities in France in regard to a popular proprietary remedy for syphilis known as Rob Boyveau-Laffecteur. It was sold as a non-mercurial compound. It was first prepared or advertised in 1780 by a war office official named Laffecteur, whose position enabled him to get it largely used in the army. Subsequently a Paris doctor named Boyveau bought a share in the business, but in time the partners separated, and both sold the Rob. Boyveau wrote a bulky volume on the treatment of syphilis, and in that he strongly praised the Rob. After the deaths of Laffecteur and Boyveau the business came into the hands of a Dr. Giraudeau, of St. Gervais. This was about the year 1829. In 1780 the Academie de Medicine had examined this preparation, and had apparently, though not formally, tolerated its sale. Their chemist, Bucquet, had been instructed specially to examine the syrup for sublimate. He reported that he could not find any, but he was by no means sure that there was none there, for he stated that he had himself added 2 grains to a bottle, and could not afterwards detect its presence. Between that time and 1829 several chemists studied the subject, and came to the conclusion that if corrosive sublimate had been added to the syrup the vegetable extractive or the molasses with which it was made so concealed it or decomposed it into calomel that it could not be detected. In 1829 Giraudeau was prosecuted for selling secret medicines, and for this offence was fined 600 francs. But the interesting feature of this trial was the testimony of Pelletier, Chevallier, and Orfila that the Rob contained no mercurial. They reported that the formula given by the maker might be the correct one, but that in that case the mixture would contain too small a quantity of active substances to possess the energetic properties claimed for it. Guaiacum and sarsaparilla were the principal ingredients, but there were also lobelia, astragalus root, several other herbs, and a little opium. The history of this discussion is related at some length in Dr. Michelon’s “Histoire Pharmacotechnique et Pharmacologique du Mercure” (1908). RED PRECIPITATE.