It seems certain that in Henry VIII’s reign the apothecaries were doing a considerable amount of medical practice, besides selling drugs. The Act of 1511 incorporating the College of Physicians and giving them the exclusive right to practise physic in London and for seven miles round, was largely used, if not intended, against apothecaries. In 1542, however, an Act was passed which rather modified the severe restrictions of the original statute, and under the new law apothecaries became more aggressive. In Mary’s reign the Physicians again got the legislative advantage, and there is a record in the archives of the College of Physicians (preserved by Dr. Goodall, who wrote “A History of the Proceedings of the College against Empiricks,” in 1684) stating that in Queen Elizabeth’s reign the President and Censors of the College summoned the Wardens of the Grocers’ Company and all the apothecaries of London and the suburbs to appear before them, “and enjoyned them that when they made a dispensation of medicine they should expose their several ingredients (of which they were composed) to open view in their shops for six or eight days that so the physicians passing by might judge of the goodness of them, and prevent their buying or selling any corrupt or decayed medicines.” The grocers and apothecaries do not appear to have raised any objection to this decree. Whether they obeyed it or not is not stated. INCORPORATION OF THE APOTHECARIES. The first Charter of Incorporation was granted to the apothecaries by James I in 1606, but this did not separate them from their old foes, the grocers. They continued their efforts, however, and with the aid of friends at Court they obtained a new Charter in 1617, which gave them an entirely independent existence as a City Guild under the title of the Society of the Apothecaries. This is the only London guild which has from its incorporation to the present time admitted only actual apothecaries to its fraternity. Another peculiarity claimed by one of the Company’s historians (Dr. J. Corfe: “The Apothecary”) is that the Guild of Apothecaries is the only City Company which is called a Society. He believes that this may be attributed to the supposed fact that the corporation was modelled on a similar association founded at Naples in 1540 under the name of Societa Scientifica. [Illustration: SIR THEODORE MAYERNE. The original painting by Rubens, of which the above is a copy, was in the collection of Dr. Mead, and was sold in 1754 for £115. It passed into the possession of the Earl of Bessborough and the Marquis of Lansdowne, and then through the hands of some dealers, and in 1848 was bought by the Royal College of Physicians for £33 12_s._ ]