The pills were to be made of equal quantities by measure of snails calcined as before, wild carrot seeds, burdock seeds, ashen-keys, hips and haws, all burnt to blackness, “or which is the same thing, till they have done smoaking.” The mixed powders to be passed through a cypress sieve, and a large spoonful or 4 oz. of best alicant soap, and a sufficiency of honey added to make pills; each ounce of the mass to be divided into sixty pills. One dram (avoirdupois) of the powder was to be taken three times a day in a large teacupful of white wine, cyder, or small punch, and half a pint of the decoction had to be drunk after each dose. If the medicine caused much pain an opiate was to be given. The bowels were to be kept regular with lenitive electuary or some other laxative. The pills were to be given in fits of gravel or suppression of urine, five every hour; or ten or fifteen might be taken daily to prevent formation of gravel stones in constitutions subject to breed them. Salt meats, red wine, and milk were to be avoided. The patient was to take as few liquids as possible, and to have but little exercise. The object aimed at was that the urine might be impregnated with the medicine, which would then dissolve the calcareous deposits. Mrs. Stephens died in 1774. The publication of her formula undoubtedly stimulated investigation into the employment of alkaline medicines in the treatment of stone, but her “cases” were not substantiated by later evidence. One in particular was that of a man who was experimented on while the proposal to buy the recipe was under consideration. He was unquestionably suffering from stone, and he soon improved and in time seemed to be quite cured after taking the remedies. After his death examination showed that the stone was still in his bladder; but it had made for itself a little sac in which it was so tightly embedded that it never caused any inconvenience. Pereira, summing up the evidence in regard to the Stephens’ treatment, says it cannot be doubted that many patients obtained relief from the remedies, “but no cure was effected; that is, no calculus was dissolved. For in the bladder of each of the four persons whose cure was certified by the trustees the stone was found after their death.” I have not traced the report of the four cases; only of the one referred to above. EARL OF ROCHESTER AS QUACK. The witty but profligate Earl of Rochester, well known in history as the boon companion of Charles II, especially in his debaucheries, frequently gave offence to that monarch by his impudence or his sarcasms. His best known epigram is that referring to Our Sovereign Lord the King Whose word no man relies on Who never said a foolish thing And never did a wise one.