So during the next four years the Duke of Gandia laboured to carry out the orders of his ecclesiastical superior, removing the only hindrances that bound him to the world. His late wife’s sister Doña Juana de Meneses acted as mother to his children. In 1548, he married his heir the Marquess Don Carlos of Lombay, at the age of eighteen years, to Doña Magdalene de Centellas y Cardona, Countess of Oliva. In 1549, he married his daughter Doña Isabella to Don Francisco de Sandoval y Rojas, Marquess of Denia and Count of Lerina. He finished the buildings of the Dominican monastery at Gandia, and of the Jesuit College which is richly endowed with houses for poor scholars, and for children of the Maranas or Jews on condition of baptism. He also obtained charters from the Lord Paul P.P. III and from Caesar Carlos V. raising this college to the rank of an university. At last, in 1550, he left his duchy of Gandia and journeyed toward Rome, escorted by a retinue of thirty servants, and his second son Don Juan de Borgia of the age of seventeen years. He had to pay the penalty of his extraordinary notoriety. On his passage through Ferrara, the reigning Duke (who himself came of Borgia stock) met him with fêtes and processions. At Florence, Duke Cosmo de’ Medici accorded a state-reception. He was going to renounce the world; and the world made a triumphal progress of his going. His desire to slink into the lowest place won him attention verging on adoration. His chagrin was undisguised. He envoyed an avant-courier to ask his superior’s leave to enter Rome by night avoiding publicity. Padre Iñigo de Loyola peremptorily refused: for the Duke of Gandia was too good an object-lesson to be thrown away. His entrance into the Eternal City, whose citizens even in 1550 revered the memory of Borgia, was like that of a king who comes into his kingdom. The Lord Paul P.P. III sent ambassadors to welcome him, and to offer lodging in the Apostolic Palace of the Vatican: but the Duke of Gandia hurried to the Jesuit College; doing obeisance at the feet of the General and Founder of the Company of Jesus. So these two unique personalities first met, whom now men call Saint Ignatius of Loyola, Saint Francis of Borgia.