of quality in the metabolic phenomena depend upon their chemical composition. In order to render tenable the hypothesis contained in the second point, it is merely necessary to show that crystals capable of imbibition can unite with one another according to certain laws. If at their first formation all crystals were isolated, if they held no relation whatever to each other, the view would leave entirely unexplained how the elementary parts of organisms, that is, the crystals in question, become united to form a whole. It is therefore necessary to show that crystals do unite with each other according to certain laws, in order to perceive, at least, the possibility of their uniting also to form an organism, without the need of any further combining power. But there are many crystals in which a union of this kind, according to certain laws, is indisputable; indeed they often form a whole, so like an organism in its entire form, that groups of crystals are known in common life by the names of flowers, trees, etc. I need only refer to the ice-flowers on the windows, or to the lead-tree, etc. In such instances a number of crystals arrange themselves in groups around others, which form an axis. If we consider the contact of each crystal with the surrounding fluid to be an indispensable condition to the growth of crystals which are not capable of imbibition, but that those which are capable of imbibition, in which the solution can penetrate whole layers of crystals, do not require this condition, we perceive that the similarity between organisms and these aggregations of crystals is as great as could be expected with such difference of substance. As most cells require for the production of their metabolic phenomena, not only their peculiar nutrient fluid, but also the access of oxygen and the power of exhaling carbonic acid, or _vice versa_; so, on the other hand, organisms in which there is no circulation of respiratory fluid, or in which at least it is not sufficient, must be developed in such a way as to present as extensive a surface as possible to the atmospheric air. This is the condition of plants, which require for their growth that the individual cells should come into contact with the surrounding medium in a similar manner, if not in the same degree as occurs in a crystal tree, and in them indeed the cells unite into a whole organism in a form much resembling a crystal tree. But in animals the circulation renders the contact of the individual cells with the surrounding medium superfluous, and they may have more compact forms, even though the laws by which the cells arrange themselves are essentially the same.