To-day, October 31, 1886, 2,490 persons have received the preventive inoculations in Paris alone. The treatment was in the first instance uniform for the great majority of the patients, notwithstanding the different conditions presented by them as to age, sex, the number of bites received, their seat, their depth, and the time which had elapsed since the occurrence of the accident. It lasted ten days, the patient receiving every day an injection prepared from the spinal marrow of a rabbit, beginning with that of fourteen days’ and ending with that of five days’ desiccation. Those 2,490 cases are subdivided according to nationality in the following manner: Russia 191 Italy 165 Spain 107 England 80 Belgium 57 Austria 52 Portugal 25 Roumania 22 United States 18 Holland 14 Greece 10 Germany 9 Turkey 7 Brazil 3 India 2 Switzerland 2 France and Algeria 1,726 The number of French persons has been considerable, amounting to 1,726, and it will be enough to confine ourselves to the category formed by them as a basis for discussing the degree of efficacy of the method. Out of the total 1,726 cases treated, the treatment has failed ten times--namely, in the following cases: The children: Lagut, Peytel, Clédière, Moulis, Astier, Videau. The woman: Leduc, seventy years old. The men: Marius Bouvier (thirty years), Clergot (thirty), and Norbert Magnevon (eighteen). I leave out of count two other persons, Louise Pelletier and Moermann, whose deaths must be attributed to their tardy arrival at the laboratory, Louise Pelletier thirty-six days, and Moermann forty-three days after they had been bitten. We have therefore ten deaths for 1,726 cases, or 1 in 170; such are, for France and Algeria, the results of the first year’s application of the method. Those statistics, taken as a whole, demonstrate the efficacy of the treatment, as proved further by the relatively large number of deaths which occurred amongst bitten persons who had not been vaccinated. FOOTNOTES: [Footnote 35: From Address delivered August 10, 1884 at the Copenhagen meeting of the International Medical Congress.] XXXIII JAMES CLERK MAXWELL 1831-1879