I believe that the latter view is the true one: I have expounded it for a number of years, and have attempted to defend it, and to work out its further details in various publications. I propose to call it the theory of “The Continuity of the Germ-plasm,” for it is founded upon the idea that heredity is brought about by the transference from one generation to another of a substance with a definite chemical, and above all, molecular constitution. I have called this substance “germ-plasm,” and have assumed that it possesses a highly complex structure, conferring upon it the power of developing into a complex organism. I have attempted to explain heredity by supposing that in each ontogeny a part of the specific germ-plasm contained in the parent egg-cell is not used up in the construction of the body of the offspring, but is reserved unchanged for the formation of the germ-cells of the following generation. It is clear that this view of the origin of germ-cells explains the phenomena of heredity very simply, inasmuch as heredity becomes thus a question of growth and of assimilation,--the most fundamental of all vital phenomena. If the germ-cells of successive generations are directly continuous, and thus only form, as it were, different parts of the same substance, it follows that these cells must, or at any rate may, possess the same molecular constitution, and that they would therefore pass through exactly the same stages under certain conditions of development, and would form the same final product. The hypothesis of the continuity of the germ-plasm gives an identical starting point to each successive generation, and thus explains how it is that an identical product arises from all of them. In other words, the hypothesis explains heredity as part of the underlying problems of assimilation and of the causes which act directly during ontogeny; it therefore builds a foundation from which the explanation of these phenomena can be attempted.