On the personal prophylaxis of plague no more need be said, but in out-of-the-way places, it not unfrequently devolves on the non-medical European to have to take measures for the protection of the indigenous community, in the absence of medical advice. To be effective, the little that can be done must be done at once, and therefore a few words on the general or public prophylaxis against the disease may not be out of place. One of the few redeeming features in the natural history of plague, is that it at first spreads very slowly. It is doubtful if, in any case, the bulk of the infections are from man to man, and it appears on the whole probable that, after the first introduction of the infection, time is usually required to admit of the thorough establishment of the disease amongst the rats before it can attain any formidable spread amongst men. During this early stage there is no great difficulty in dealing with the disease, and hence it is absolutely of the most vital importance to obtain information as to the occurrence of the first cases. In the case of these first attacks, whether imported or apparently of local origin, no measures of disinfection and isolation can be too rigorous; but the people should be made to clearly understand that except at their own express desire and by their own enforcement, compulsion in such matters will be at once relaxed should the disease unfortunately gain a firm footing in their midst. As a matter of fact it is unfortunately too true that there is really very little that can be done to any purpose, when once the disease has fairly fixed itself on the susceptible mass of an oriental urban population, and above all things it is worse than useless to attempt to enforce sanitary measures by compulsion, as it only leads to the concealment of extent and localisation of the disease, and to organised obstruction to all remedial measures attempted by those in authority. It should be the duty of a civilised government to place at the disposal of the population every possible means of combating the disease which our superior knowledge and civilisation enables us to recommend, but it should be made absolutely clear that these benefits of civilisation are there to be simply taken or left, as they please. In the cases of measures particularly liable to be mistrusted, such as inoculation, it may even be well to charge a small fee for the operation, to be remitted of course in cases when the patient can show that he is really impecunious. The joy of getting to windward of the too credulous official by a pardonable understatement of finances, would be a temptation hard to resist by the average Oriental, and there is no harm in writing out such a receipt; for the folks who require Hibernian driving of this sort cannot read, and it was one of their countrymen who could not only read, but think very much to the purpose, who suggested the expedient to the writer.