Eleven successful cases, including three of operation for cataract, one double iridectomy, one removal of tumour from lid, and three for convergent strabismus. In cases of intolerance of light it acts like magic.—L. ii./84,911. In papillomata of larynx, interior painted with 20 per cent. solution of hydrochlorate of Cocaine once, in five minutes was able to introduce the forceps four times and remove large portions of tumours without patient experiencing any pain or subsequent shock.—L. ii./84,912. In quinsy, a 20 per cent. solution useful to paint fauces.—Pr. xli. 47. Coca and Cocaine are said to have a deleterious action on the voice, slackening and deadening the vocal cords through the paralysis of the extensor muscles. The aphony produced is painless.—Th. Gaz. May, 1889,353. Physiological effects on the eye.—L. ii./84,911. Seven eye cases under its influence.—Med. Rec. (N. Y.) 1884,510. Use in the nasal cavity, cotton wool soaked in 2 per cent. solution applied at the end of a probe in over forty cases, including hypertrophy of the nasal mucous membrane (twenty-seven cases cauterized), acute coryza, nasal polypus and hay-fever, all having marked swelling of the nasal mucous membrane, both from chronic and acute causes; in every case there was complete subsidence of the turgescence of the membrane and the sinuses were emptied of their blood.—Med. Rec. (N.Y.) 1884,533. Cocaine solution applied to a blistered surface anæsthetizes the part.—B.M.J. i./85,300. Solution painted on or injected into piles relieves the pain of operating on them.—B.M.J. i./85,227.