The painless removal of urethral caruncles.—B.M.J. ii./85,153; and of epithelioma.—L. i./87,56. In obstetrics, several valuable applications.—Pr. xxxiv. 65; L. ii./87,754, 1061; ii./90,474. The oleate is useless, except for sores on penis and anus.—Pr. xxxiv. 451. Hypodermic injections apt to be followed by faintness.—Pr. xxxiv. 450. Gonorrhœa, acute, 2 per cent. solution injected relieves the pain.—Pr. xxxiv. 222. Rectal and prostatic pains relieved by ½-grain suppositories.—Pr. xxxiv. 128. Summary of its effects on the eye, viz., dilatation of pupils, constriction of small peripheral vessels, paralysis of accommodation, and enlargement of the palpebral fissure; the effect is local only, by paralysing the endings of the sensory nerves, and irritating the sympathetic nerves.—Pr. xxxiv. 1. Dysmenorrhœa, the pain of, removed by painting the cervix with 4 per cent. solution.—B.M.J. ii/85,399. After lithotrity, ½ an ounce of 4 per cent. solution injected for painless removal of fragments.—Pr. xxxiv. 128. In labour pain attending the dilatation of the os in primiparæ relieved by painting the os and cervix with 12 per cent. solution.—B.M.J. ii./85,473. In supra-orbital neuralgia, a 10 or 20 per cent. solution in oil of cloves rubbed into the part affords immediate relief; with summary of its medical uses.—Pr. xxxiv. 59; M.R. 1884,516. In sea-sickness, several cases, ¹⁄₁₆ grain doses every two or three hours in aqueous solution were successful. A girl of 18 had been sick 24 hours before it was tried; she had a double dose every half-hour with “truly magical effect.”—L. ii./85,451; B.M.J. ii./85,627. German and Russian recommendations of its use in sea sickness.—L. ii./85,912. Sea sickness effectually checked by two lozenges each containing ¹⁄₁₂ grain of hydrochlorate of cocaine taken when first threatened, and two more in twenty minutes. One grain doses in solution also effectual.—P. J. 1886,712.—B.M.J. ii./87,1236. Thimble-shaped pessaries, composed of cocaine and oil of theobroma, relieved the pains of the first stage of labour, when inserted into the dilated os uteri. B.M.J. ii./85,1140,1159. Morphine habit of three years’ standing, 8½ grains taken during three days was successful in curing.—B.M.J. ii./85,1112. Counteracting effects unsatisfactory.—L. i./89,287. Poisonous effects attributed to local use in fourteen eye cases and three hypodermic injections.—B.M.J. ii./85,983. Vaginismus, ointment and pessaries of cocaine useful.—B.M.J. ii./88,720,817; B.M.J. Supp. ii./90,30; Relief temporary only.—B.M.J. ii./88,790. Cases of fainting when solution of cocaine salt was applied to the eye.—B.M.J. ii./85,1060; i./86,67. Also after hypodermic injection.—Pr. xxxiv. 450. In eye operations, the diminished elasticity produced by cocaine may be a source of inconvenience.—L. ii./85,1158.