present, may be combated by the subsequent use of strong coffee or tea, as before. We have seen this plan succeed in several cases.——_Lesions._ These, like the symptoms, vary. In some cases there are redness and inflammation of the stomach and intestines, and turgescence of the vessels of the lungs and brain; in others, these appearances are either slight or wholly wanting. Wherever there has been much cerebral disturbance, traces of congestion are usually discernible. _Detec., Tests, &c._ The identification of the pure alkaloids is extremely simple; but their detection, when combined with organic and colouring matters, is a task of considerable difficulty. One or other of the following plans may be adopted for this purpose:—— 1. (Merck.) The matter under examination is digested, for several hours, with concentrated acetic acid, added in sufficient quantity to produce a strongly acid reaction; the fluid portion is then strained from the insoluble matter, and the latter being washed with water acidulated with acetic acid, the mixed liquors are gently evaporated to dryness in a water bath; the residuum of the evaporation is boiled first with rectified spirit, and next with rectified spirit acidulated with acetic acid; the mixed liquors are again evaporated, the residuum redissolved or diluted with distilled water, and carbonate of soda or potassa added to feebly alkaline reaction, and the whole, after evaporation to the consistence of a syrup, set aside to repose for 24 hours; it is now again diluted with water, filtered, and the insoluble portion washed with cold distilled water, and digested with concentrated acetic acid; this last solution is diluted with distilled water, and decoloured with pure blood-charcoal (if it be necessary); the fluid, either at once, or after cautious evaporation, may then be tested for the alkaloids, in the usual manner. The charcoal previously used should also be tested in the way described below. This method answers admirably with all the NON-VOLATILE ALKALOIDS, and may be applied to the stomach and viscera, and their contents, and to food, &c., in cases of poisoning.