Cooley's Cyclopædia of Practical Receipts and Collateral Information in the Arts, Manufactures, Professions, and Trades..., Sixth Edition, Volume ICooley, Arnold James
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Cooley's Cyclopædia of Practical Receipts and Collateral Information in the Arts, Manufactures, Professions, and Trades..., Sixth Edition, Volume I
Cooley, Arnold James
Formulas, recipes, etc.; Industrial arts -- Dictionaries; Technology -- Dictionaries
=ACONITIA, CRYSTALLISED.= C_{27}H_{40}NO_{10}. Exhaust the root of wild
aconite, carefully picked and powdered, with very strong alcohol, to which
1 per cent. of tartaric acid has been added. Distil at a gentle heat, and
sheltered from the air, to recover the alcohol. Treat the extract with
water to separate all the fatty and resinous matters. The solution which
contains the aconite in the state of acid tartrate is first shaken with
ether to remove colouring matters, and then the alkaloid is set free by
the addition of alkaline bicarbonate, until the cessation of
effervescence. A fresh treatment with ether of this alkaline solution
removes the alkaloid, which crystallizes upon the concentration of the
ethereal liquid, with an addition of petroleum spirit. The crystals are
colourless tables, rhombic or hexagonal, according to the modifications
produced principally in the acute angles. Crystallized aconitia is soluble
in alcohol, ether, benzine, and chloroform; insoluble in petroleum oils
and glycerine.
ACONITIA NITRATE, CRYSTALLISED. Crystallised aconitine q. s.; nitric acid,
sp. gr. 1·442, q. s. Saturate the nitric acid with the aconitine and
evaporate. Voluminous crystals are easily obtained (from ‘Formulæ for New
Medicaments adopted by the Paris Pharmaceutical Society’).——‘Pharm.
Journal.’ Owing to the decomposition which this alkaloid undergoes in the
animal organism, as well as to its liability to decompose during the
process of evaporation, and exposure to the air, it often becomes
extremely difficult, if not impossible, to obtain it in a separate state
in conducting a _post-mortem_ examination. The physiological effects seem
to furnish the most prominent and characteristic evidence of its presence
in such cases, or at any rate these may serve as a valuable guide to the
toxicologist.
Uncrystallised aconitia is sometimes contaminated with delphinia, as well
as with aconella, another constituent of aconite root. For the dissection
of these see ALKALOIDS. One fiftieth of a grain of aconitia is stated to
have killed a dog.
_Antidotes._ See ACONITE.
=ACONITIC ACID.= (Identical with _Pyrocitric Acid_.) An acid extracted by
Peschier from _aconitum napellus_, and by Bracconnot from _equisetum
fluviatile_. It exists in these plants chiefly in the form of aconitate of
calcium.
_Properties._ A white, colourless, semi-crystalline mass.
=ACONITINA.= See ACONITIA.
=ACONITINE.= See ACONITIA.
=ACONI′TUM.= [L.] Aconite. The pharmacopœial name of _aconitum
napellus_(see _below_).
=Aconitum Ferox.= (Ind. P.) _Habitat_. Temperate and sub-Alpine Himalaya,
at 10,000 to 14,000 feet elevation, from Gurhwal to Sikkim.
_Officinal part._ The dried root (_Aconiti ferocis Radix_), in common with
those of other Himalayan species, viz., _aconitum napellus_, _a.
palmatum_, and _a. luridum_, constitutes the drug well known in the
bazaars of Upper India under the Hindostani name of _Bish_ or _Bikh_.
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