Curiosities of Medical ExperienceMillingen, J. G. (John Gideon)
Philosophy
Curiosities of Medical Experience
Millingen, J. G. (John Gideon)
Medicine
As I have elsewhere observed, various are the theories that have been
entertained in regard to digestion, but the experiments of Dr. Beaumont
seem to have proved beyond a doubt, that this operation is due to the
action of the gastric juice, with which he was enabled to produce
artificial digestion. Having obtained one ounce of this solvent from the
stomach of his patient, he put into it a solid piece of recently-boiled
beef, weighing three drams, and placed the vessel that contained it in a
water bath heated to 100 deg. In forty minutes digestion had commenced on
the surface of the meat; in fifty minutes, the fluid was quite opake and
cloudy, the external texture began to separate and become loose; in sixty
minutes, chyme began to form. At 1 p.m. (two hours after the commencement
of the experiment), the cellular substance was destroyed, the muscular
fibres loose and floating about in fine small threads very tender and
soft. In six hours they were nearly all digested--a few fibres only
remaining. After the lapse of ten hours, every part of the meat was
completely digested. The artificial digestion by these experiments appears
to be but little slower than the natural process--they also demonstrate
the influence of the temperature, and the quantity of the solvent
secretion. Having obtained from St. Martin two ounces of gastric juice, he
divided this quantity into two equal portions, and laid in each an equal
quantity of masticated roast beef. One he placed in a water bath at the
temperature of 99 deg. Farh.--and left the other exposed to the open air
at the temperature of 34 deg.; a third similar portion of meat he kept in a
phial, with an ounce of cold water. An hour after the commencement of the
experiment, St. Martin had finished his breakfast, which consisted of the
same meat with biscuit, butter, and coffee. Two hours after the meat had
been put into the phial, the portion in the warm gastric juice was as far
advanced in chymification as the food in the stomach; the meat in the cold
gastric juice was less acted on, and that in the cold water only slightly
macerated. In two hours and forty-five minutes from the time that the
experiment was begun, the food in the stomach was completely digested, the
stomach empty, while even at the end of six hours the meat in the gastric
juice was only half digested. Dr. Beaumont, therefore, having procured 12
drams of fresh gastric juice, added now a portion to each of the phials
containing meat and gastric juice, and to a portion of the half-digested
food which he had withdrawn from the stomach two hours after the
commencement of the experiment, and which had not advanced towards
solution. After eight hours' maceration, the portions of meat in the cold
gastric juice, and in the cold water, were little changed, but, from the
time of the addition of the fresh gastric juice, digestion went on rapidly
in the other phials, which were kept at the proper heat, and at the end of
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