4th. Partial closure of the eyelids in animals born of parents in which that state of the eyelids had been caused either by section of the cervical sympathetic nerve, or the removal of the superior cervical ganglion. 5th. Exophthalmia in animals born of parents in which an injury to the restiform body had produced that protrusion of the eyeball. This interesting fact I have witnessed a good many times, and seen the transmission of the morbid state of the eye continue through four generations. In these animals, modified by heredity, the two eyes generally protruded, although in the parents usually only one showed exophthalmia, the lesion having been made in most cases only on one of the corpora restiformia. 6th. Haematoma and dry gangrene of the ears in animals born of parents in which these ear-alterations had been caused by an injury to the restiform body near the nib of the calamus. 7th. Absence of two toes out of the three of the hind leg, and sometimes of the three, in animals whose parents had eaten up their hind-leg toes which had become anaesthetic from a section of the sciatic nerve alone, or of that nerve and also of the crural. Sometimes, instead of complete absence of the toes, only a part of one or two or three was missing in the young, although in the parent not only the toes but the whole foot were absent (partly eaten off, partly destroyed by inflammation, ulceration, or gangrene.) 8th. Appearance of various morbid states of the skin and hair of the neck and face in animals born of parents having had similar alterations in the same parts, as effects of an injury to the sciatic nerve. These results[64] have been independently vouched for by two of Brown-Séquard's former assistants--Dr. Dupuy, and the late Professor Westphal. Moreover, his results with regard to epilepsy have been corroborated also by Obersteiner[65]. I may observe, in passing, that this labour of testing Brown-Séquard's statements is one which, in my opinion, ought rather to have been undertaken, if not by Weismann himself, at all events by some of his followers. Both he and they are incessant in their demand for evidence of the transmission of acquired characters; yet they have virtually ignored the foregoing very remarkable statements. However, be this as it may, all that we have now to do is to consider what the school of Weismann has had to say with regard to these experiments on the grounds of general reasoning which they have thus far been satisfied to occupy. [64] For Professor Weismann's statement of and discussion of these results see _Essays_, vol. i. p. 313. [65] _Oesterreichische medicinische Jahrbücher_, 1875, 179.