Those who have followed the researches of the American school will be aware that, after it had been found in certain insects that the spermatozoa were of two kinds according as they contained or did not contain the accessory chromosome, E.B. Wilson succeeded in proving that the sperms possessing this accessory body were destined to form FEMALES on fertilisation, while sperms without it form males, the eggs being apparently indifferent. Perhaps the most striking of all this series of observations is that lately made by T.H. Morgan (Morgan, "Proc. Soc. Exp. Biol. Med." V. 1908, and von Baehr, "Zool. Anz." XXXII. page 507, 1908.), since confirmed by von Baehr, that in a Phylloxeran two kinds of spermatids are formed, respectively with and without an accessory (in this case, DOUBLE) chromosome. Of these, only those possessing the accessory body become functional spermatozoa, the others degenerating. We have thus an elucidation of the puzzling fact that in these forms fertilisation results in the formation of FEMALES only. How the males are formed--for of course males are eventually produced by the parthenogenetic females--we do not know. If the accessory body is really to be regarded as bearing the factor for femaleness, then in Mendelian terms female is DD and male is DR. The eggs are indifferent and the spermatozoa are each male, OR female. But according to the evidence derived from a study of the sex-limited descent of certain features in other animals the conclusion seems equally clear that in them female must be regarded as DR and male as RR. The eggs are thus each either male or female and the spermatozoa are indifferent. How this contradictory evidence is to be reconciled we do not yet know. The breeding work concerns fowls, canaries, and the Currant moth (Abraxas grossulariata). The accessory chromosome has been now observed in most of the great divisions of insects (As Wilson has proved, the unpaired body is not a universal feature even in those orders in which it has been observed. Nearly allied types may differ. In some it is altogether unpaired. In others it is paired with a body of much smaller size, and by selection of various types all gradations can be demonstrated ranging to the condition in which the members of the pair are indistinguishable from each other.), except, as it happens, Lepidoptera. At first sight it seems difficult to suppose that a feature apparently so fundamental as sex should be differently constituted in different animals, but that seems at present the least improbable inference. I mention these two groups of facts as illustrating the nature and methods of modern genetic work. We must proceed by minute and specific analytical investigation. Wherever we look we find traces of the operation of precise and specific rules.