Here would be the upper part of the animal--that great mass of bones that we spoke of as the spine (_a_, Fig. 1). Here I should have the alimentary canal (_b_, Fig. 1). Here I should have the heart (_c_, Fig. 1); and then you see, there would be a kind of double tube, the whole being inclosed within the hide; the spinal marrow would be placed in the upper tube (_a_, Fig. 1), and in the lower tube (_d d_, Fig. 1), there would be the alimentary canal (_b_), and the heart (_e_); and here I shall have the legs proceeding from each side. For simplicity's sake, I represent them merely as stumps (_e e_, Fig. 1). Now that is a horse--as mathematicians would say--reduced to its most simple expression. Carry that in your minds, if you please, as a simplified idea of the structure of the horse. The considerations which I have now put before you belong to what we technically call the "Anatomy" of the horse. Now, suppose we go to work upon these several parts,--flesh and hair, and skin and bone, and lay open these various organs with our scalpels, and examine them by means of our magnifying-glasses, and see what we can make of them. We shall find that the flesh is made up of bundles of strong fibres The brain and nerves, too, we shall find are made up of fibres, and these queer-looking things that are called ganglionic corpuscles. If we take a slice of the bone and examine it, we shall find that it is very like this diagram of a section of the bone of on ostrich, though differing, of course, in some details; and if we take any part whatsoever of the tissue, and examine it, we shall find it all has a minute structure, visible only under the microscope. All these parts constitute microscopic anatomy or "Histology." These parts are constantly being changed; every part is constantly growing, decaying, and being replaced during the life of the animal. The tissue is constantly replaced by new material; and if you go back to the young state of the tissue in the case of muscle, or in the case of skin, or any of the organs I have mentioned, you will find that they all come under the same condition. Every one of these microscopic filaments and fibres (I now speak merely of the general character of the whole process)--every one of these parts--could be traced down to some modification of a tissue which can be readily divided into little particles of fleshy matter, of that substance which is composed of the chemical elements, carbon, hydrogen, oxygen, and nitrogen, having such a shape as this (Fig. 2). These particles, into which all primitive tissues break up, are called cells. If I were to make a section of a piece of the skin of my hand, I should find that it was made up of these cells. If I examine the fibres which form the various organs of all living animals, I should find that all of them, at one time or other, had been formed out of a substance consisting of similar elements; so that you see, just as we reduced the