[Footnote 50: In Mr. Gulick's last paper (_Journal of Linn. Soc. Zool._, vol. xx. pp. 189-274) he discusses the various forms of isolation above referred to, under no less than thirty-eight different divisions and subdivisions, with an elaborate terminology, and he argues that these will frequently bring about divergent evolution without any change in the environment or any action of natural selection. The discussion of the problem here given will, I believe, sufficiently expose the fallacy of his contention; but his illustration of the varied and often recondite modes by which practical isolation may be brought about, may help to remove one of the popular difficulties in the way of the action of natural selection in the origination of species.] CHAPTER VII ON THE INFERTILITY OF CROSSES BETWEEN DISTINCT SPECIES AND THE USUAL STERILITY OF THEIR HYBRID OFFSPRING Statement of the problem--Extreme susceptibility of the reproductive functions--Reciprocal crosses--Individual differences in respect to cross-fertilisation--Dimorphism and trimorphism among plants--Cases of the fertility of hybrids and of the infertility of mongrels--The effects of close interbreeding--Mr. Huth's objections--Fertile hybrids among animals--Fertility of hybrids among plants--Cases of sterility of mongrels--Parallelism between crossing and change of conditions--Remarks on the facts of hybridity--Sterility due to changed conditions and usually correlated with other characters--Correlation of colour with constitutional peculiarities--The isolation of varieties by selective association--The influence of natural selection upon sterility and fertility--Physiological selection--Summary and concluding remarks.