After stopping a while at Maulmain and Singapore, the missionaries arrived at Macao in November, 1836, and here commenced immediate preparation to engage in the gospel work. Their first son was born shortly before their arrival at Macao. They called him Lewis, for his father. On the 29th of October the second son was born, who was named Ryland Keeling. With these two babes around her, the labor of the mother was materially increased and essentially changed. Her own family required more of her care, and gave her less time and opportunity to do good abroad. Yet, with her family as it was, she is said to have found much time for the usual purposes of missionary life, and was zealously engaged in plans for the spiritual improvement of those around her. While at Macao her heart was cheered by hearing that God was pouring out his Spirit in her own dear land; that he was converting sinners, and among them some who had been her intimate friends. Her own sisters were led to give their hearts to God; and when the intelligence crossed the deep, and was told in the hearing of the sad and perhaps almost discouraged missionary, her joy knew no bounds. It was as a cup of cold water to one dying with thirst; and the letter which brought the tidings was read over and over again, and frequently bathed in tears of joy. Her letters to her sisters express her deep interest in their spiritual welfare. She pleads with them by the love of Jesus that they be faithful to the Savior of their souls and walk worthy of Him who has bought them with his own blood. To do this, she urges them to study the word of God, and be constant in the closet, and meditate much upon spiritual things, and watch and guard the heart from temptation and sin. Nor does she forget to recommend the cultivation of a missionary spirit, but, with all the eloquence of a sister's love, urges them to do good as they have opportunity.