In much of his work Needham was associated with Buffon, and the results of their experiments fitted in admirably with the great French naturalist's hypothesis of "organic molecules," according to which, life is the indefeasible property of certain indestructible molecules of matter, which exist in all living things, and have inherent activities by which they are distinguished from not living matter. Each individual living organism is formed by their temporary combination. They stand to it in the relation of the particles of water to a cascade, or a whirlpool; or to a mould, into which the water is poured. The form of the organism is thus determined by the reaction between external conditions and the inherent activities of the organic molecules of which it is composed; and, as the stoppage of a whirlpool destroys nothing but a form, and leaves the molecules of the water, with all their inherent activities intact, so what we call the death and putrefaction of an animal, or of a plant, is merely the breaking up of the form, or manner of association, of its constituent organic molecules, which are then set free as infusorial animalcules. It will be perceived that this doctrine is by no means identical with _Abiogenesis_, with which it is often confounded. On this hypothesis, a piece of beef, or a handful of hay, is dead only in a limited sense. The beef is dead ox, and the hay is dead grass; but the "organic molecules" of the beef or the hay are not dead, but are ready to manifest their vitality as soon as the bovine or herbaceous shrouds in which they are imprisoned are rent by the macerating action of water. The hypothesis therefore must be classified under Xenogenesis, rather than under Abiogenesis. Such as it was, I think it will appear, to those who will be just enough to remember that it was propounded before the birth of modern chemistry, and of the modern optical arts, to be a most ingenious and suggestive speculation. But the great tragedy of Science--the slaying of a beautiful hypothesis by an ugly fact--which is so constantly being enacted under the eyes of philosophers, was played, almost immediately, for the benefit of Buffon and Needham.